Choose the appropriate word to fill in the blank.

My Father is confined _______ the house.

The correct sentence is:

My Father is confined to the house.

Here's why:

• The preposition "to" is used to indicate a location or state.

• In this case, "to the house" indicates that the father is restricted to the house, possibly due to illness or other reasons.

Therefore, "to" is the appropriate word to fill in the blank.