Development of Medicines
1. This question has 2 part(s).
1.1. Higher Tier Only
Monoclonal antibodies can be used to determine blood hormone levels.
Pregnancy test strips use monoclonal antibodies.
The hormone HCG is produced in the placenta in pregnant women.
The kidneys excrete HCG.
Figure 1 shows three pregnancy test strips.
Figure 1
(i) Which test strip would belong to a woman who is not pregnant?
(1)
(ii) Pregnancy testing uses monoclonal antibodies.
Give two other uses of monoclonal antibodies.
(2)
1.2. Hepatitis B is an infectious viral disease which infects the liver.
A double-blind trial was carried out to assess the effectiveness of using monoclonal antibodies to treat patients with a hepatitis B infection.
During the trial referred, a number of patients were admitted to the hospital because they felt unwell.
Information about these patients is shown in Figure 2.
Treatment | % of patients within each group admitted to hospital with hepatitis B |
|---|---|
Group A: Placebo | 6.2 |
Group B: Monoclonal antibody | 1.8 |
Figure 2
3 000 patients were involved in the trial.
Half the patients (Group A) were given the placebo.
Half the patients (Group B) were given the monoclonal antibody being tested.
(i) Outline how a double-blind trial would be carried out.
(3)
Higher Tier Only
(ii) Explain how injecting a patient, suffering from hepatitis B, with a specific monoclonal antibody will help in their treatment.
(2)
(iii) Using the data in Figure 6, calculate the number of patients admitted to hospital with hepatitis B during the trial.
(2)
Ai এর মাধ্যমে
১০ লক্ষ+ প্রশ্ন ডাটাবেজ
প্র্যাকটিস এর মাধ্যমে নিজেকে তৈরি করে ফেলো
উত্তর দিবে তোমার বই থেকে ও তোমার মত করে।
সারা দেশের শিক্ষার্থীদের মধ্যে নিজের অবস্থান যাচাই
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