1.1. The coronary arteries supply the heart muscle tissue with blood.

Fig. 1 shows a coronary artery with a blockage. 

Fig. 1

Explain the effect this blockage could have on heart muscle cells.

1.2. A blocked coronary artery can lead to coronary heart disease. 

Table 1 shows information about blood flow through coronary arteries in two people.

Person X was diagnosed with coronary heart disease while person Y does not have coronary heart disease.

Table 1

(i) Explain the difference in blood flow through the coronary arteries for persons X and Y.

[1]

(ii) Calculate the volume of blood flowing through the coronary arteries of person X in 1 hour.

Give your answer in dm³.

[2]

1.3. A blockage of the coronary artery can be caused by fatty deposits called plaques. Drugs called statins can be taken to help prevent a blockage. 

Fig. 2 shows the effects of the treatment of one person with four different statins (A, B, C and D) over a period of 10 years. The arrows show when each new treatment was started.

Fig. 2

Determine a conclusion on the effectiveness of the statin treatments in reducing the risk of coronary heart disease for this person.

1.4. The data was used to generate a report, with the claim: "Coronary heart disease can be cured by statins".

Evaluate the claim.