Genetic Mutations (A Level only)
1. This question has 4 part(s).
1.1. Different mutations have different effects on an organism.
Give the letter that corresponds to the statement(s) in Table 1 that correctly describes the effect of a mutation in the exon of a gene.
Table 1
A | A substitution always results in a change to the encoded amino acid. |
B | An addition may change more than one amino acid. |
C | An inversion will result in a change in the number of DNA bases. |
D | A deletion will not result in a frame shift. |
1.2. Chronic myeloid leukemia (CML) is a type of cancer that affects white blood cells. CML is caused when a section of chromosome 9 breaks off and fuses with chromosome 22.
Name the type of mutation that occurs in chronic myeloid leukemia.
1.3. A type of malignant tumour cell divides every 6 hours.
Starting with one malignant tumour cell, and assuming none die, calculate the number of tumour cells that will be present after 8 weeks. Give your answer in standard form.
1.4. Give three factors that increase the chances of genetic mutation.
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