1.1. Table 1 shows information about deaths from malaria in a particular area of Africa.

Table 1

Complete Fig. 1 using data from Table 1.

Fig. 1

1.2. Malaria is spread by the female Anopheles mosquito when they break through the skin of an uninfected person during a blood meal.

Explain how the skin acts as a mechanical barrier against disease.

1.3. Once the mechanical barrier formed by the skin is broken, the malaria pathogen enters the blood.

Outline the defence mechanism that will come into effect once a pathogen enters the blood.